An experimental study was conducted on a 3/10 large-scale model of a two-span post-tensioned slab bridge. The model was directly erected on columns without column caps; in addition to uniformly distributed longitudinal post-tensioned tendons, band-shaped transverse prestressing tendon bundles were arranged in the anchorage zones above the columns. AASHTO lane loads were applied to observe the short-term and long-term responses of the model structure under dead and live loads, and the results were compared with finite element analysis.