To address the poor corrosion and fatigue resistance of the suspenders in tied arch bridges, a method using carbon fiber-reinforced polymer (CFRP) suspenders on tied arch bridges is proposed. The mechanical properties of tied arch structures and suspenders under different replacement principles are studied, and the equal area principle is selected as the material replacement method. The static responses of structures supported by CFRP suspenders and steel strand suspenders under different loads are compared and ana-lyzed using finite element software. The differences in stress variation between the two approaches are relatively slight, and CFRP can effectively replace steel strands as the material for tied arch bridges. The load-bearing capacities of the suspenders are compared and analyzed based on the “short hanger effect”. Compared with full-bridge suspender replacement, single-suspender replacement is more effective and feasible for real bridge applications. An actual engineering case using CFRP suspenders on tied arch bridges is analyzed, which provides new insights for the development of tied arch bridges.