Suspension bridge, as the bridge with the largest span, has been developed rapidly in China, but the research on the anti-corrosion of the cable system of the superstructure of Suspension bridge has not achieved very satisfactory results, especially the anti-corrosion of the main cable as the lifeline of Suspension bridge. At present, bridge cables mainly rely on cable replacement to solve the anti-corrosion and safety performance issues of the cables. Suspension bridge's slings, anchorages, stay cables, etc. have all had the technology of cable replacement, but the main cable of Suspension bridge has not seen the technology and examples of cable replacement. This paper mainly introduces the structural design of the replaceable main cable of Suspension bridge and its saddles, cable clamps, and splay sleeves, and focuses on the design of key components, cable clamps, and their related tests. Explain the feasibility of achieving interchangeable main cables and anti-corrosion of main cables