Aiming at the structural safety of nuclear power plant containment anchorage system, the finite element analysis software ANSYS is used to analyze and compare the force of OVM15R-37C anchor plate and the optimized OVM15R-37CP anchor plate. The results show that the optimized anchor plate not only has better performance, but also is more economical than the former. Based on the experimental results of load transfer of OVM15R-37CP anchor plate and the stress distribution of concrete in anchoring area, the safety of structure and the rationality of finite element simulation are verified.