The cables of a double tower cable-stayed bridge are generally symmetrically arranged relative to the main tower, with anchor heads or cable saddles installed on the main tower and anchor heads installed inside the main beam for anchoring. The middle of the main span is a cable free zone, which is usually compensated for by placing prestressed steel tendons in this area during design. In this paper, the author puts forward the concept of cable span transfer coupler of cable stayed bridge, which effectively solves the tension problem of cable free zone of cable stayed bridge with two towers or more. In the design of Donghe River Crossing Bridge in Hohhot City, for the first time, the outermost cables of two towers are continuously arranged, thus avoiding the existence of cable free zone, greatly simplifying the anchorage structure, and achieving good results