In recent years, the use and promotion of prefabricated assembly construction in China have been rapidly advancing, especially when combined with prestressing technology and Ultra-High-Performance Concrete (UHPC) as a new material to solve the connection and node construction between assembly components. It has started to be widely applied in developed coastal areas of China. This paper focuses on the node connection part of the prefabricated assembly construction used in the Shanghai Riverside Channel project. It explores the application of UHPC material in the assembly process and verifies the reliability of the relevant connection nodes through various experiments. The successful application of this research has been implemented in the Shanghai Riverside Tunnel project.