At present, the maintenance of long-span Suspension bridge involves less engineering practice of cable clamp replacement, and its replacement faces many engineering problems that need to be solved urgently. Based on the example of cable clamp replacement project of a long-span Suspension bridge, this paper introduces the selection and design essentials of temporary facilities for cable clamp replacement of a long-span Suspension bridge; And the construction process of rapid cable clamp replacement was emphasized, which has been proven by engineering practice to be safe and effective in achieving rapid cable clamp replacement. At the same time, this practice can provide reference for the design and construction of similar bridge type cable clamp replacement