As a new type of spatial structure, the large-span asymmetrical saddle-shaped cable network structure has the characteristics of novel shape, large span and less steel, and is mainly used for large public buildings or sports venues. In this paper, based on the roof of Panjin Stadium, a large number of simulation calculations and scheme comparison are carried out in view of the structural characteristics of the large-span asymmetrical saddle-shaped cable network structure, and the construction method of "ground assembly, synchronous lifting and integral tensioning" is proposed. The tensioning test was carried out on the 1∶10 structure model to verify the correctness of the simulation calculation and the feasibility of the construction method. Five key technologies of the construction method, such as the whole process simulation calculation analysis, cable cutting, synchronous lifting technology, integral tensioning technology and construction monitoring technology, are studied deeply. The research results have been successfully applied in the construction of Panjin Stadium roof, Foshan Furniture City roof and Xuzhou stadium roof space cable structure, and have achieved good results, which can provide useful reference for the tensioning of such structures