Fully prefabricated bridge is a set of high efficiency, low carbon, environmental protection bridge construction technology, this paper will focus on the practice of this technology. Based on the development situation at home and abroad, the prefabrication and assembly technology of superstructure is briefly introduced. Then, the prefabrication technology of substructure is introduced, including the common joint method of prefabrication columns at home and abroad and the seismic performance of prefabrication columns. Finally, the full prefabrication technology is summarized.