Prestressed high-strength threaded steel bars are widely used in the construction of Bridges, grid buildings, docks, tunnels and dykes, etc. With the continuous development of building structures in our country, the installation of large structures and their components is also increasing, and the requirements for the strength and diameter of prestressed high-strength threaded steel bars are also increasing. This paper introduces the application of large-diameter high-strength threaded steel bar developed by Liuzhou Overwem Machinery Co., Ltd. in the full scale project test of Hong Kong-Zhuhai-Macao Bridge preset cap and the construction process of supporting anchor products. The application of high-strength threaded steel bars has promoted the technical progress of the steel industry and machinery manufacturing industry, and has great significance for the construction of Bridges and other fields at home and abroad, and has better economic benefits and far-reaching social benefits.