The anchoring force loss of prestressed anchor cable will cause its anchoring effect to weaken or even fail, which will bring great harm to engineering safety. In the process of program design, studying the influence factors such as anchor system, anchor cable structure, anchor cable spacing, anchor cable tonnage and rock and soil properties, and taking certain design measures can effectively restrain, reduce or even eliminate the influence of anchor force loss, which has important theoretical and engineering practice significance for the design, construction and safe operation of anchor engineering, and improve the economic and social benefits of the project.