In China, cable-stayed bridge has been developed and widely used in recent 20 years because of its straddling ability and unique aesthetic effect. However, due to the complexity of the cable-stayed bridge structure system itself, the defects of the material itself, the construction technology, methods, quality problems, environmental corrosion, vehicle overload and the maintenance management is not in place during the operation period, the cable of the built cable-stayed bridge has more or less appeared various diseases. This not only affects the performance and normal operation of the bridge, but also reduces the safety margin of the main structure of the bridge, bringing hidden dangers in safety and defects in durability to the bridge. In this paper, the existing cable diseases of cable-stayed Bridges in China are investigated and analyzed in detail, and the use status of cable cables of cable-stayed Bridges and the main diseases such as PE sheath cracking, cable wire corrosion fracture, anchor corrosion, fatigue cracking are summarized, and the causes of the diseases are analyzed. On this basis, the corresponding maintenance strategies and measures are put forward, including the suggestions in design, construction, operation and management.