The development of bridge construction towards large spans, deep waters, nearshore areas, and steep mountains faces enormous technological challenges. After reviewing the technical difficulties of a batch of bridges such as the Sutong Bridge, the technological innovation of large-span bridges was summarized, and the key technical issues of large-span bridges were proposed. The concept of integrated design was proposed for small and medium-sized bridges with large quantities and wide areas; Analyzed the hot issues of bridge disaster prevention and reduction technology; The strategy of bridge Structural health monitoring and maintenance is discussed